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英国伦敦弗朗西斯·克里克研究所蛋白质生物化学、分子生物学方向博士后招聘

时间:2019-07-17 13:37   编辑:本站

英国伦敦弗朗西斯·克里克研究所蛋白质生物化学、分子生物学方向博士后招聘

 招聘简介:  职称:培训研究员-莫洛德索夫实验室  地点:伦敦米德兰路弗朗西斯克里克研究所  合同:定期(4年),全职  薪酬:具有竞争优势,受技能和经验的影响  空缺ID:10846  简短的摘要  弗朗西斯克里克研究所的机械生物学和生物物理学小组正在寻找一位高素质的生物化学家加入我们的跨学科团队。 MaximMolodtsov领导,我们研究分子原理和力量,导致精确和大规模的DNA重排和准确的DNA分离,我们使用广泛的单分子技术,包括力谱,单分子成像和单分子FRET。 我们还继续开发新工具,以了解移动和重组DNA的机器的机制。 在过去,我们对驱动DNA组织和细胞骨架重排的机制进行了重要发现,并开发了新的成像物理工具。   候选人应具有蛋白质生物化学和分子生物学的扎实背景。 预计它们具有强大的出版记录和对定量生物物理方法和/或单分子方法的浓厚兴趣。

不需要显微镜,生物物理和/或力谱的经验,但欢迎。   英文原文:  Jobtitle:PostdoctoralTrainingFellowMolodtsovLaboratory  Location:TheFrancisCrickInstitute,MidlandRoad,London  Contract:Fixed-term(4years),fulltime  Salary:Competitivewithbenefits,subjecttoskillsandexperience  VacancyID:10846  Shortsummary  ThemechanobiologyandbiophysicsgroupattheFrancisCrickInstituteisloo,weinvestigatemolecularprinciplesandforcesthatleadtopreciseandlarge-scaleDNArearrangementsandaccurateDNAsegregationandweusebroadrangeofsingle-moleculetechniquesincludingforcespectroscopy,nizationandcytoskeletonrearrangementsaswellasdevelopednewphysicaltoolsforimaging.  Candidatesshonquantitativebiophysicalmethodsand/,biophysicsand/orforcespectroscopyisnotrequiredbutwelcome.  Projectscope  Positionsareavailableintwoareas:(1)Microtubule-basedcytoskeletonrearrangementsandchromosomemovements;(2)DNAorganizationandsegregationduringcelldivision.  Thesuccessfulcandidatewilluseinvitroassaystorecons,theywillusemulti-wavelengthTIRFmicroscopyand/orsingle-moleculeimagingincludingsingle-moleculeFRETand/oropticaltrappingaswellasadvanceddataprocessing.  Theprojectwillbenefitfromclosecollaborationswithleadingexpertsinsingle-moleculeimagingandforce-spectroscopybothwithinthegroupandexternallyattheCrickandPhysicntributetointerdisciplinaryteamthatworksondevelopingnewtoolsforinvestigatingreorganizationofcytoskeletonandDNAbymotorandnon-motorcomplexesthatgenerateandrespondtomechanicalforces.  Aboutus  TheFrancisCrickInstituteisabiomedicaldiscoveryinstitutededicatecoveriesintonewwaystoprevent,diagnoseandtreatillnessessuchascancer,heartdisease,stroke,infections,andneurodegenerativediseases.  Anindependentorganisation,itsfoundingpartnersaretheMedicalResearchCouncil(MRC),CancerResearchUK,Wellcome,UCL(UniversityCollegeLondon),ImperialCollegeLondonandKingsCollegeLondon.  TheCrickwasformedin2015,andin2016itmovedintoanewstate-of-the-artbuildingincentralLondonwhichbringstogether1500scientistsandsupportstaffworkingcollaborativelyacrossdisciplines,makingitthebiggestbiomedicalresearchfacilityunderinonebuildinginEurope.  Ttion;developingemergingtalentandexportingittherestoftheUK;publicengagement;andhelpingturndiscoveriesintotreatmentsasquicklyaspossibletoimprovelivesandstrengthentheeconomy.  oIfyouareinterestedinapplyingforthisrole,pleaseapplyviaourwebsite.  oTheclosingdateforapplicationsis20June2019at23:30.  AlloffersofemploymentaresubjecttosuccessfulsecurityscreeningandcontinuouseligibilitytoworkintheUnitedKingdom.关注微信公众号。